SPOTLESS Regimen for Acne, Blemishes and Breakouts Designed for Teens and Young Adults

Item Number UNRS001

Retail $89.00 Retail Value of $112. Regimen for teens and young adults helps clear and prevent acne breakouts.

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Real Results
Eliminate acne, deep clean pores and controls appearance of oil and shine with this simple, two-step Regimen. With breakthrough BPO2 technology, this teen and young adult acne treatment delivers more oxygen and Benzoyl Peroxide to pores, killing acne bacteria from Day 1 of treatment.

Potent Ingredients

  • Daily Acne Wash: 5% Benzoyl Peroxide penetrates pores to eliminate teen and young adult acne before it starts.
  • Acne Clearing Treatment: Breakthrough BPO2 Technology delivers more oxygen and Benzoyl Peroxide to the pores to eliminate acne. The unique dual-chamber delivery system delivers 2.5% Benzoyl Peroxide in tandem with our boosting gel. This combination ensures maximum efficacy of Benzoyl Peroxide, reducing the number and severity of acne and helping prevent new ones from forming.

SPOTLESS Regimen includes:
SPOTLESS Daily Acne Wash (125 mL / 4.2 Fl.Oz. U.S.)
SPOTLESS Acne Clearing Treatment (50 mL / 1.7 Fl.Oz. U.S.)


During the acne cycle, acne begins to form days or even weeks before reaching skin’s surface. Everyone’s skin is different, but with daily use, you’ll notice visible improvement in acne in as soon as one day, and with daily use, continue to see improvement in one to four weeks.

Clinical data is based on twice-daily use of SPOTLESS Daily Acne Wash and Acne Clearing Treatment for 8 weeks.*

Improvement in size (height) and redness of inflammatory acne:
87% of participants noticed improvement in 1 Day
100% of participants noticed improvement in 1 Week

Improvement after 8 weeks:
97% of participants experience improvement in the appearance of overall lesion appearance
90% of participants experience improvement in the appearance of skin oiliness/shininess
90% of participants experience improvement in the appearance of skin clarity
90% of participants experience improvement in the appearance of skin smoothness

*Percent based on teen and young adult participants in an 8-week U.S. clinical and consumer study. Results may vary depending on multiple factors: Age, gender, skin type and condition, concomitant products used, healthy history, location, lifestyle and diet.


Use once daily and increase to twice daily as tolerated. If bothersome dryness or peeling occurs, reduce application to once a day or every other day.

Step 1: Wet skin with lukewarm water.

Step 2: Using fingertips, apply a thin, even layer of SPOTLESS Daily Acne Wash and massage over entire face for 90 seconds, avoiding all contact with eyes.

Step 3: Rinse thoroughly and pat dry.

Step 4: Dispense 1-2 pumps of SPOTLESS Acne Clearing Treatment into palm and blend evenly.

Step 5: Cover the entire affected area with a thin, even layer of product. Do not rinse off.

Wash hands after application to help avoid staining or bleaching fabrics. If going outside, apply sunscreen after using these products. If irritation or sensitivity develops, stop use of both products and ask a doctor.

SPOTLESS Daily Acne Wash


ACTIVE INGREDIENT: Benzoyl Peroxide 5%
INACTIVE INGREDIENTS: Water, Polyacrylamide, C13-14 Isoparaffin, Glycerin, Jojoba Esters, Sodium Glycolate, Carbomer, Diethylhexyl Sodium Sulfosuccinate, Cocamidopropyl Dimethylamine, Cocamidopropyl Betaine, Laureth-7, Sodium Chloride, Sodium Citrate, Sodium Hydroxide, Propanediol, Ethylhexylglycerin, Phenoxyethanol.

SPOTLESS Acne Clearing Treatment


ACTIVE INGREDIENT: Benzoyl Peroxide 2.5%
INACTIVE INGREDIENTS: Water, Glycereth-18 Ethylhexanoate, Glycereth-18, Glycerin, Butylene Glycol, Vaccinium Angustifolium (Blueberry) Fruit Extract, Sodium Hyaluronate, Polygonum Cuspidatum Root Extract, Bisabolol, Allantoin, Zingiber Officinale (Ginger) Root Extract, Octenidine HCL, Fragrance, Phytosteryl/Octyldodecyl Lauroyl Glutamate, Methyl Methacrylate Crosspolymer, Myristyl Alcohol, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Cyclopentasiloxane, Butyl Hydroxycyclohexane Carboxylate, Dimethyl Isosorbide, Carbomer, Polyglyceryl-2 Isostearate, Sorbitan Oleate, Diethylhexyl Sodium Sulfosuccinate, Cetyl Hydroxyethylcellulose, Cyclohexasiloxane, Polysorbate 80, Xanthan Gum, Hydroxyphenyl Propamidobenzoic Acid, Ascorbyl Palmitate, Tocopherol, PCA, Sodium Citrate, Citric Acid, Sodium Hydroxide, Propanediol, Pentylene Glycol, Isohexadecane, Caprylyl Glycol, 1,2-Hexanediol, Decylene Glycol, Hydroxyacetophenone, Propylene Glycol, Ethylhexylglycerin, Hexylene Glycol, Phenoxyethanol, Citral, Citronellol, Limonene, Linalool, Titanium Dioxide (CI 77891), Mica, Tin Oxide, Blue 1 (CI 42090), Red 33 (CI 17200), Violet 2 (CI 60725).



I am using the SPOTLESS Regimen and my breakouts are getting worse. What should I do?
The acne cycle is also influenced by hormones, stress and other physiological and environmental factors, all of which may contribute to flare-ups. Having a few more acne breakouts when you begin using the SPOTLESS Regimen may be normal. However, if you have been using the products for over a month and you are still experiencing increased breakouts, please contact the RF Connection at rfconnection@rodanandfields.com for assistance.

I’m using the SPOTLESS Regimen and my skin is dry. What should I do?
Slight tightness or mild redness may indicate that your skin is adjusting to the ingredients in the skincare Regimen. This is a common occurrence and may last up to two weeks. If you experience dryness while using the SPOTLESS Regimen, layer a moisturizer over SPOTLESS Acne Clearing Treatment, such as SOOTHE Sensitive Skin Treatment or SOOTHE Moisture Replenishing Cream.

How long should I use the SPOTLESS Regimen?
You can use this skincare Regimen for as long as needed, but just because your skin is clear, it doesn’t mean it’s time to stop. Continuous use of the Regimen helps maintain skin clarity. Once your skin has been acne-free for an extended period of time, you may consider shifting to once-a-day use of the SPOTLESS Regimen.

What products can I use during the off times while I ramp up the SPOTLESS Regimen?
We recommend that you use gentle cleansers, moisturizers and sunscreens as you ramp up to using the SPOTLESS Regimen twice a day. Avoid other products containing acne ingredients such as Benzoyl Peroxide and Salicylic Acid, Retinoids, Alpha-hydroxy Acids like Glycolic, or any scrubs and mechanical brushes, as they can result in irritation. The SOOTHE Regimen is a good option for your skincare Regimen.

Can the SPOTLESS Regimen be used on my body?
You may use the SPOTLESS Regimen to address body acne as well. Ramp up as directed to twice a day as needed to control acne breakouts on the body. When using the SPOTLESS Regimen on the body, apply a lightweight moisturizer if skin feels dry. Because Benzoyl Peroxide can bleach fabrics, opt instead for white clothing, linens and towels.

What is the BPO2 Technology in the SPOTLESS Regimen?
Oxygen and Benzoyl Peroxide is acne bacteria’s worst nightmare — when it’s actually able to make its way into the pores. The problem with traditional acne-fighting products is that Benzoyl Peroxide is distributed unevenly across skin’s surface, limiting its effectiveness. Unlike these traditional products, our proprietary BPO² Technology dissolves and evenly disperses Benzoyl Peroxide to deliver more of this acne-fighting ingredient and oxygen into pores. The result? More effective acne treatment and prevention, starting Day 1.

I am allergic to Benzoyl Peroxide. Can I use the SPOTLESS Regimen?
Both products in the SPOTLESS Regimen contain Benzoyl Peroxide. Unfortunately, if you are allergic to Benzoyl Peroxide, you will not be able to use the SPOTLESS Regimen.

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