Can you substitute Active Hydration Serum for Night Renewing Serum when using the AMP MD Derma-Roller?

No. Active Hydration Serum and Night Renewing Serum have different benefits. The REDEFINE AMP MD Derma-Roller has been clinically tested and patented with the Night Renewing Serum to firm the appearance of the skin. Active Hydration Serum can be used in addition to Night Renewing Serum to amplify the effects, however, it should not be used to replace Night Renewing Serum.

The great news is that they can be used together to amplify effects. Just apply Active Hydration Serum after rolling with the REDEFINE AMP MD and before the REDEFINE Night Renewing Serum.