Acne can be persistent, but smart skincare makes a visible difference. Dermatologists consistently recommend benzoyl peroxide for its ability to kill acne-causing bacteria, clear clogged pores, and calm inflammation. With a consistent, structured approach, benzoyl peroxide can be your best ally in achieving blemish-free, healthy-looking skin.
Start your journey to clearer skin. Shop dermatologist-developed routines now!
What Makes Benzoyl Peroxide Work
Benzoyl peroxide (BPO) is a topical treatment recognized for its antibacterial and exfoliating properties. It targets Cutibacterium acnes, the bacteria behind most breakouts, while clearing excess oil and dead skin cells. Its non-antibiotic nature makes it safe for long-term use.
Why It Belongs in Every Acne Routine
When used correctly, benzoyl peroxide helps to:
- Eliminate acne-causing bacteria
- Minimize irritation and redness
- Prevent pore buildup for fewer breakouts
- Support smoother, balanced-looking skin
Consistency is essential; start slow, build gradually, and let the results compound over time.
How to Build a Benzoyl Peroxide Routine
Step 1: Cleanse
Use a gentle, refreshing cleanser that removes oil without stripping skin. The SPOTLESS Daily Acne Wash preps pores with oxygen-infused benzoyl peroxide for better absorption and fast results.
Step 2: Treat
Apply a thin layer of SPOTLESS Acne Clearing Treatment, featuring 2.5% BPO with proprietary BPO2 Technology, a breakthrough that boosts oxygen delivery and combats bacteria deep in pores.
Step 3: Hydrate
Even acne-prone skin needs hydration. Choose a lightweight, non-comedogenic moisturizer to balance skin and reduce dryness caused by actives.
Step 4: Protect
Always finish with SPF. Because benzoyl peroxide increases sun sensitivity, using a broad-spectrum SPF 30+, like the one in the UNBLEMISH Matte Defense, helps maintain results.
4-Week Ramp-Up Schedule
| Week | Frequency | Focus |
| 1 | Every other day | Help skin adjust |
| 2 | Once daily | Build tolerance |
| 3 | Twice daily | Maintain if minimal irritation |
| 4+ | Adjust as needed | Continue for consistent results |
How to Avoid Irritation
- Start with 2.5% BPO if new to active ingredients.
- Apply a pea-sized amount across affected areas, not individual spots.
- Follow with moisturizer.
- Avoid layering with retinoids or acids unless dermatologist-approved.
- Allow the product to fully dry before contact with fabrics to prevent bleaching.
Visible Results Over Time
Expect gradual but measurable improvement:
- Week 2–3: Fewer active breakouts
- Week 4–6: Reduced redness, oil control
- Week 8+: Clearer texture and refined pores
Rodan + Fields Benzoyl Peroxide Formulas
Knock Out Acne for Good! Give acne the ultimate 1-2 punch with our powerful 2-step SPOTLESS Regimen, designed specifically for teens and young adults. This award-winning routine clears existing blemishes, prevents new breakouts, and keeps shine under control thanks to our breakthrough BPO₂ Technology.
DETAILS
What’s Included:
- Spotless Daily Acne Wash — 65 mL / 2.2 fl oz
- Spotless Acne Clearing Treatment — 2 × 10 mL / 2 × 0.33 fl oz
What It Is: A dermatologist-developed acne routine for teenage and young adult skin. This 2-step system works to eliminate blemishes, unclog pores, and control excess oil, leaving skin clearer, smoother, and more balanced.
Why You’ll Love It: Consistency is key, and this daily acne treatment delivers fast, visible results. It helps reduce redness and discomfort while restoring confidence with a cleaner, healthier-looking complexion.
KEY CONCERNS
Teen + Young Adult Acne • Blemishes • Breakouts
SUITABLE FOR
All skin types
KEY BENEFITS
- Clears acne and prevents new breakouts
- Deep cleans pores and removes impurities
- Controls excess oil and reduces unwanted shine
- Promotes a smoother, healthier-looking complexion
INGREDIENT SPOTLIGHT
Benzoyl Peroxide 2.5%. Delivers oxygen deep into pores to kill acne-causing bacteria and reduce pimples from Day 1.
BOOST YOUR SAVINGS + RESULTS
SPOTLESS 60-Day Regimen Save 20% when you purchase the complete 60-day set instead of buying products individually.
HOW TO USE
Use once daily, avoiding the eye area. Gradually increase to twice daily (AM + PM) as tolerated. If dryness or peeling occurs, reduce to once daily or every other day.
Step 1: Cleanser – Spotless Daily Acne Wash Wet skin with lukewarm water. Apply a thin layer and gently massage for 90 seconds. Rinse thoroughly and pat dry.
Step 2: Treatment – Spotless Acne Clearing Treatment Dispense 1–2 pumps into your palm. Apply evenly over the affected area — do not rinse.
New to SPOTLESS? [View the Ramp-Up + Usage Guide ]
⚠️ Warning: Wash hands after use to avoid bleaching fabrics. Apply sunscreen before sun exposure. If irritation occurs, discontinue use and consult a doctor.
Defeat Breakouts Fast!
Give acne the ultimate 1–2 punch with our SPOTLESS 2-Step Regimen, designed specifically for teens and young adults. This dermatologist-developed, 60-day supply helps clear existing blemishes, prevent new breakouts, and control oil + shine with our breakthrough BPO₂
Technology — for visibly clearer, more balanced skin every day.
Typical Use: Twice daily, morning and evening.
DETAILS
What It Is:
A simple yet powerful 2-step skincare system that deeply cleans pores, eliminates acne, and balances oil production. Ideal for young, breakout-prone skin, this routine keeps your complexion fresh, smooth, and shine-free.
Why You’ll Love It:
Consistent use helps reduce redness, shrink blemishes, and calm irritation — all while improving your overall skin clarity. Gain confidence and comfort with our award-winning acne treatment that delivers fast, visible results.
Item Number: UNRS001
KEY CONCERNS
Teen + Young Adult Acne • Blemishes • Breakouts
SKIN TYPE
Suitable for all skin types
KEY BENEFITS
- Clears acne and prevents future breakouts
- Deep cleans pores and removes impurities
- Reduces excess oil + shine for a matte finish
- Promotes a clearer, healthier-looking complexion
HERO INGREDIENT
Benzoyl Peroxide 2.5%
A scientifically proven acne fighter that delivers oxygen deep into pores to eliminate acne-causing bacteria starting on Day 1.
HOW TO USE
Use once daily, avoiding the eye area. Gradually increase to twice daily (AM + PM) as tolerated.
If dryness or peeling occurs, reduce to once a day or every other day.
Step 1: Cleanser – Spotless Daily Acne Wash
Wet skin with lukewarm water.
Apply a thin layer and massage for 90 seconds.
Rinse thoroughly and pat dry.
Step 2: Treatment – Spotless Acne Clearing Treatment
Dispense 1–2 pumps into your palm.
Apply evenly to the affected area — do not rinse.
New to SPOTLESS? [View the Ramp-Up + Usage Guide]
⚠️ Warning: Wash hands after application to avoid fabric bleaching.
If exposed to sunlight, apply sunscreen afterward.
If irritation or sensitivity occurs, stop use and consult a doctor.
Clear Skin, Smooth Confidence Break up with breakouts, and wrinkles! Our powerful 4-step UNBLEMISH Regimen targets adult acne while visibly minimizing fine lines, pores, and uneven texture for clearer, smoother, younger-looking skin.
Recommended Usage: Twice daily, morning and evening.
DETAILS
What’s Included:
- Unblemish Refining Acne Wash — 65 mL / 2.2 fl oz
- Unblemish Clarifying Toner — 60 mL / 2 fl oz
- Unblemish Dual Intensive Acne Treatment — 2 × 10 mL / 2 × 0.33 fl oz
- Unblemish Invisible Matte Defense Broad Spectrum SPF 30 — 15 mL / 0.5 fl oz
What It Is: A dermatologist-inspired, gentle yet highly effective skincare system designed to fight both acne and aging. It clears existing blemishes, prevents future breakouts, and improves the look of pores, firmness, and tone.
Why You’ll Love It: This routine removes excess oil, dirt, and impurities while exfoliating dead skin cells to reveal a clearer, refined complexion. Plus, it hydrates and smooths fine lines, perfect for adults managing both acne and aging skin concerns.
Item Number: UNRG30D
KEY CONCERNS
Adult Acne + Blemishes • Excess Oil • Uneven Tone + Texture • Clogged or Enlarged Pores • Blackheads
SUITABLE FOR
All skin types
KEY BENEFITS
- Reduces and prevents breakouts
- Removes excess oil + deep cleans pores
- Exfoliates dead skin for smoother texture
- Minimizes the look of fine lines + enlarged pores
- Helps balance + strengthen skin’s barrier
POWERFUL INGREDIENTS
Salicylic Acid – Gently exfoliates + clears congested pores. Hyaluronic Acid – Deeply hydrates + visibly firms skin. 2.5% Benzoyl Peroxide – Fights blemishes + prevents new breakouts. Ceramides – Reinforce the skin barrier + lock in moisture.
HOW TO USE
Use twice daily (AM + PM) — avoid the eye area.
Step 1: Cleanser – Unblemish Refining Acne Wash. Massage a dime-sized amount onto wet skin for 30–60 seconds. Rinse thoroughly and pat dry.
Step 2: Toner – Unblemish Clarifying Toner Swipe evenly over face using a cotton pad. Allow to dry before applying treatment.
Step 3: Treatment – Unblemish Dual Intensive Acne Treatmen.t Dispense 1–2 pumps into hand and blend evenly over the face.
Step 4 (AM Only): Moisturizer + SPF – Unblemish Invisible Matte Defense Broad Spectrum SPF 30 Apply a dime-sized amount to face and neck. Reapply every 2 hours when exposed to sunlight.
Clear your skin and restore youthful smoothness with this powerful 4-step, 60-day skincare regimen designed to target both adult acne and visible signs of aging. This dual-action system helps prevent breakouts while minimizing pores, refining texture, and reducing the look of fine lines for a balanced, radiant complexion.
Recommended Usage: Use twice daily, morning and evening.
DETAILS
What It Is:
A gentle yet effective daily skincare system that addresses two top skin concerns — acne and aging. It works to clear and prevent blemishes while improving uneven skin tone, restoring firmness, and refining overall texture.
Why You’ll Love It:
This multi-benefit regimen deeply cleanses to remove dirt, oil, and impurities while preventing new breakouts from forming. At the same time, it smooths fine lines, minimizes enlarged pores, and supports a healthier, firmer complexion.
Item Number: HUNRJ001
KEY CONCERNS
Adult Acne + Blemishes • Excess Oil • Uneven Tone + Texture • Clogged or Enlarged Pores • Blackheads
SUITABLE FOR
All skin types
KEY BENEFITS
- Reduces acne and prevents new breakouts
- Removes dirt, oil, and dead skin for clearer pores
- Smooths and refines uneven texture
- Minimizes fine lines and enlarged pores
- Strengthens the skin barrier for long-lasting hydration
POWERFUL INGREDIENTS
Salicylic Acid: Gently exfoliates dead skin cells and clears clogged pores.
Hyaluronic Acid: Provides deep hydration while visibly firming the skin.
2.5% Benzoyl Peroxide: Targets acne-causing bacteria to treat and prevent blemishes.
Ceramides: Strengthen the skin barrier and lock in essential moisture.
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Reveal your best skin. Try the science-backed Rodan + Fields acne regimen today.
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