An unexpected breakout can happen anytime, and when it does, fast-acting care makes all the difference. Benzoyl peroxide spot treatments are clinically tested solutions formulated to target acne at its source, helping visibly reduce blemishes while minimizing new breakouts.
What Is Benzoyl Peroxide?
Benzoyl peroxide (BPO) is a dermatologist-developed ingredient used to target acne-causing bacteria and help clear blocked pores. It works on contact by reducing excess oil, removing dead surface cells, and supporting a visibly smoother texture.
Why It Remains a Dermatology Essential
Despite emerging technologies in acne care, benzoyl peroxide remains a cornerstone treatment thanks to its consistent, proven results. It continues to perform across diverse skin types for three main reasons:
- Targets acne-causing bacteria without contributing to antibiotic resistance.
- Helps minimize clogged pores and surface buildup.
- Supports visibly clearer skin with continued use.
With millions affected by acne worldwide, reliable and accessible options like benzoyl peroxide remain essential for proactive, everyday skincare.
Expert Tips for Use
Apply a small amount of product directly onto clean, dry blemishes once or twice a day. Avoid overlapping strong actives like retinol or acids in the same routine.
Recommended best practices:
- Cleanse with a gentle, non-stripping formula.
- Wait 5–10 minutes before applying treatment.
- Hydrate after application to maintain comfort.
- Avoid alcohol-based products or abrasive scrubs.
- Allow product to dry fully before bed, benzoyl peroxide may bleach fabrics.
Building an Acne-Safe Routine
Benzoyl peroxide works best within a consistent, dermatologist-developed regimen designed for skin balancing and barrier support.
Simple routine:
- Cleanser: Gentle foaming or creamy cleanser
- Treatment: Apply benzoyl peroxide to active blemishes
- Moisturizer: Lightweight, non-comedogenic hydration
- Sunscreen (AM only): Broad-spectrum SPF 30+
Consistency leads to visible improvement. With continued use, skin looks clearer, smoother, and more balanced over time.
Rodan + Fields – Benzoyl Peroxide Spot Treatments
Knock Out Acne for Good! Give acne the ultimate 1-2 punch with our powerful 2-step SPOTLESS Regimen, designed specifically for teens and young adults. This award-winning routine clears existing blemishes, prevents new breakouts, and keeps shine under control thanks to our breakthrough BPO₂ Technology.
DETAILS
What’s Included:
- Spotless Daily Acne Wash — 65 mL / 2.2 fl oz
- Spotless Acne Clearing Treatment — 2 × 10 mL / 2 × 0.33 fl oz
What It Is: A dermatologist-developed acne routine for teenage and young adult skin. This 2-step system works to eliminate blemishes, unclog pores, and control excess oil, leaving skin clearer, smoother, and more balanced.
Why You’ll Love It: Consistency is key, and this daily acne treatment delivers fast, visible results. It helps reduce redness and discomfort while restoring confidence with a cleaner, healthier-looking complexion.
KEY CONCERNS
Teen + Young Adult Acne • Blemishes • Breakouts
SUITABLE FOR
All skin types
KEY BENEFITS
- Clears acne and prevents new breakouts
- Deep cleans pores and removes impurities
- Controls excess oil and reduces unwanted shine
- Promotes a smoother, healthier-looking complexion
INGREDIENT SPOTLIGHT
Benzoyl Peroxide 2.5%. Delivers oxygen deep into pores to kill acne-causing bacteria and reduce pimples from Day 1.
BOOST YOUR SAVINGS + RESULTS
SPOTLESS 60-Day Regimen Save 20% when you purchase the complete 60-day set instead of buying products individually.
RESULTS*
| Result | Timeframe | % of Users |
| Less oiliness | After 1 use | 87% |
| Smaller lesion size | 5 days | 100% |
| Reduced redness | 5 days | 97% |
| Fewer breakouts | 5 days | 95% |
| Improved overall appearance | 6 weeks | 97% |
| Less shine | 8 weeks | 100% |
*Based on an 8-week US Clinical and Consumer Study
HOW TO USE
Use once daily, avoiding the eye area. Gradually increase to twice daily (AM + PM) as tolerated. If dryness or peeling occurs, reduce to once daily or every other day.
Step 1: Cleanser – Spotless Daily Acne Wash Wet skin with lukewarm water. Apply a thin layer and gently massage for 90 seconds. Rinse thoroughly and pat dry.
Step 2: Treatment – Spotless Acne Clearing Treatment Dispense 1–2 pumps into your palm. Apply evenly over the affected area — do not rinse.
New to SPOTLESS? [View the Ramp-Up + Usage Guide ]
⚠️ Warning: Wash hands after use to avoid bleaching fabrics. Apply sunscreen before sun exposure. If irritation occurs, discontinue use and consult a doctor.
Defeat Breakouts Fast!
Give acne the ultimate 1–2 punch with our SPOTLESS 2-Step Regimen, designed specifically for teens and young adults. This dermatologist-developed, 60-day supply helps clear existing blemishes, prevent new breakouts, and control oil + shine with our breakthrough BPO₂
Technology — for visibly clearer, more balanced skin every day.
Typical Use: Twice daily, morning and evening.
DETAILS
What It Is:
A simple yet powerful 2-step skincare system that deeply cleans pores, eliminates acne, and balances oil production. Ideal for young, breakout-prone skin, this routine keeps your complexion fresh, smooth, and shine-free.
Why You’ll Love It:
Consistent use helps reduce redness, shrink blemishes, and calm irritation — all while improving your overall skin clarity. Gain confidence and comfort with our award-winning acne treatment that delivers fast, visible results.
Item Number: UNRS001
KEY CONCERNS
Teen + Young Adult Acne • Blemishes • Breakouts
SKIN TYPE
Suitable for all skin types
KEY BENEFITS
- Clears acne and prevents future breakouts
- Deep cleans pores and removes impurities
- Reduces excess oil + shine for a matte finish
- Promotes a clearer, healthier-looking complexion
HERO INGREDIENT
Benzoyl Peroxide 2.5%
A scientifically proven acne fighter that delivers oxygen deep into pores to eliminate acne-causing bacteria starting on Day 1.
RESULTS*
| Result | Timeframe | % of Participants |
| Less oiliness | After 1 use | 87% |
| Improved lesion size | 5 days | 100% |
| Reduced redness | 5 days | 97% |
| Less acne overall | 5 days | 95% |
| Improved skin appearance | 6 weeks | 97% |
| Less shine | 8 weeks | 100% |
*Based on an 8-week US Clinical and Consumer Study. Individual results may vary depending on skin type, age, and lifestyle.
HOW TO USE
Use once daily, avoiding the eye area. Gradually increase to twice daily (AM + PM) as tolerated.
If dryness or peeling occurs, reduce to once a day or every other day.
Step 1: Cleanser – Spotless Daily Acne Wash
Wet skin with lukewarm water.
Apply a thin layer and massage for 90 seconds.
Rinse thoroughly and pat dry.
Step 2: Treatment – Spotless Acne Clearing Treatment
Dispense 1–2 pumps into your palm.
Apply evenly to the affected area — do not rinse.
New to SPOTLESS? [View the Ramp-Up + Usage Guide]
⚠️ Warning: Wash hands after application to avoid fabric bleaching.
If exposed to sunlight, apply sunscreen afterward.
If irritation or sensitivity occurs, stop use and consult a doctor.
Clear Skin, Smooth Confidence Break up with breakouts — and wrinkles! Our powerful 4-step UNBLEMISH Regimen targets adult acne while visibly minimizing fine lines, pores, and uneven texture for clearer, smoother, younger-looking skin.
Recommended Usage: Twice daily, morning and evening.
DETAILS
What’s Included:
- Unblemish Refining Acne Wash — 65 mL / 2.2 fl oz
- Unblemish Clarifying Toner — 60 mL / 2 fl oz
- Unblemish Dual Intensive Acne Treatment — 2 × 10 mL / 2 × 0.33 fl oz
- Unblemish Invisible Matte Defense Broad Spectrum SPF 30 — 15 mL / 0.5 fl oz
What It Is: A dermatologist-inspired, gentle yet highly effective skincare system designed to fight both acne and aging. It clears existing blemishes, prevents future breakouts, and improves the look of pores, firmness, and tone.
Why You’ll Love It: This routine removes excess oil, dirt, and impurities while exfoliating dead skin cells to reveal a clearer, refined complexion. Plus, it hydrates and smooths fine lines, perfect for adults managing both acne and aging skin concerns.
Item Number: UNRG30D
KEY CONCERNS
Adult Acne + Blemishes • Excess Oil • Uneven Tone + Texture • Clogged or Enlarged Pores • Blackheads
SUITABLE FOR
All skin types
KEY BENEFITS
- Reduces and prevents breakouts
- Removes excess oil + deep cleans pores
- Exfoliates dead skin for smoother texture
- Minimizes the look of fine lines + enlarged pores
- Helps balance + strengthen skin’s barrier
POWERFUL INGREDIENTS
Salicylic Acid – Gently exfoliates + clears congested pores. Hyaluronic Acid – Deeply hydrates + visibly firms skin. 2.5% Benzoyl Peroxide – Fights blemishes + prevents new breakouts. Ceramides – Reinforce the skin barrier + lock in moisture.
RESULTS
Based on an 8-week clinical study*:
| Result | Percentage of Participants |
| Had less acne | 97% |
| Had less oily skin | 93% |
| Had smoother skin | 93% |
| Had more radiant skin | 83% |
| Had clearer skin | 76% |
*Individual results may vary based on age, gender, skin type, and routine consistency.
HOW TO USE
Use twice daily (AM + PM) — avoid the eye area.
Step 1: Cleanser – Unblemish Refining Acne Wash. Massage a dime-sized amount onto wet skin for 30–60 seconds. Rinse thoroughly and pat dry.
Step 2: Toner – Unblemish Clarifying Toner Swipe evenly over face using a cotton pad. Allow to dry before applying treatment.
Step 3: Treatment – Unblemish Dual Intensive Acne Treatmen.t Dispense 1–2 pumps into hand and blend evenly over the face.
Step 4 (AM Only): Moisturizer + SPF – Unblemish Invisible Matte Defense Broad Spectrum SPF 30 Apply a dime-sized amount to face and neck. Reapply every 2 hours when exposed to sunlight.
Clear your skin and restore youthful smoothness with this powerful 4-step, 60-day skincare regimen designed to target both adult acne and visible signs of aging. This dual-action system helps prevent breakouts while minimizing pores, refining texture, and reducing the look of fine lines for a balanced, radiant complexion.
Recommended Usage: Use twice daily, morning and evening.
DETAILS
What It Is:
A gentle yet effective daily skincare system that addresses two top skin concerns — acne and aging. It works to clear and prevent blemishes while improving uneven skin tone, restoring firmness, and refining overall texture.
Why You’ll Love It:
This multi-benefit regimen deeply cleanses to remove dirt, oil, and impurities while preventing new breakouts from forming. At the same time, it smooths fine lines, minimizes enlarged pores, and supports a healthier, firmer complexion.
Item Number: HUNRJ001
KEY CONCERNS
Adult Acne + Blemishes • Excess Oil • Uneven Tone + Texture • Clogged or Enlarged Pores • Blackheads
SUITABLE FOR
All skin types
KEY BENEFITS
- Reduces acne and prevents new breakouts
- Removes dirt, oil, and dead skin for clearer pores
- Smooths and refines uneven texture
- Minimizes fine lines and enlarged pores
- Strengthens the skin barrier for long-lasting hydration
POWERFUL INGREDIENTS
Salicylic Acid: Gently exfoliates dead skin cells and clears clogged pores.
Hyaluronic Acid: Provides deep hydration while visibly firming the skin.
2.5% Benzoyl Peroxide: Targets acne-causing bacteria to treat and prevent blemishes.
Ceramides: Strengthen the skin barrier and lock in essential moisture.
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Limited-Time Offer: Free full-size product with any $199+ order. Shop Now
