Dr Tim Falla has worked in dermatological research and development for 30 years, developing novel technologies, Rx and OTC drugs and award-winning skincare products. His work has resulted in more than 40 patents and over 100 peer reviewed publications including 25 related to Rodan and Fields research. Proprietary skincare ingredients developed for the company have targeted the signs of aging, pigmentation, inflammation, rosacea, acne and hydration. Working closely with Drs Rodan and Fields, since 2008, Dr Falla has created technologies based on natural products, synthetic molecules and novel forms of traditional ingredients such as vitamin A and benzoyl peroxide.
Prior to Rodan + Fields Dr Falla worked in biotech developing some of the first peptides to be used in skincare and dermatological products while researching the role of these molecules in innate immunity. Dr Falla’s early work was in anti-infectives with the identification of novel bacterial targets, development of new topical antibiotics and the creation of peptide therapeutics.
Dr Falla gained his PhD at the Universities of Cardiff and Oxford for which he developed a PCR diagnostic for bacterial meningitis in children which was subsequently adopted globally. He received post-doctoral research fellowships at the University of British Columbia, Canada and Leeds University, UK. He is widely published, in addition to original research papers he has authored several book chapters, review articles and his research has been presented at international conferences such as American Academy of Dermatology, Society of Investigative Dermatology, American Society of Microbiology and at Gordon Research Conferences.
Selected Publications
- Efficacy and tolerability of a novel facial serum. Craw J.S, Falla T, Ong D, Butani S. Clin. Dermatol. J. 2022; 7 (1).
- Accelerated barrier repair in human skin explants induced with a plant-derived PPAR- activating complex via cooperative interactions. Majewski G., Craw J., Falla T. J. Clin. Cos. Invest. Derm. 2021; 14: 1271-1293.
- Novel interpenetrating polymer network provides significant and long-lasting improvements in hydration to the skin from different body areas. T. Falla, K. Rodan, K. Fields, R. Bianchini, C. Mahon, C. Skobowiat. J. Cosmet. Dermatol .2019; 00: 1-8.
- Immediate and long-lasting benefits in hydration from body moisturizer utilizing an interpenetrating polymer network. K. Rodan, K. Fields, D. Ong, T. Falla. 2019 American Academy of Dermatology Annual Meeting, Washington, DC, March 1-5, 2019.
- Lipase, IL-1β, CAMP factor and beyond: Insights from artificial 3D skin model experiments into pathogenesity of Propionibacterium acnes to acne vulgaris. I. Dekio, K. Rodan, K. Fields, J.S. Craw, T.J. Falla, Y. Murakami. 24th World Congress of Dermatology, Milan, Italy, 10 – 15 June, 2019
- Evaluation of topical dermatologics containing L-ascorbic acid and its esters on MelanodermTM. O. Dueva- Koganov, C.M. Crane, T. Oswald, C. Skobowiat, R. Bianchini, C. Mahon, and T. Falla. 77th Annual Meeting Society of Investigative Dermatology, Chicago, IL, 8-11 May, 2019.
- Characterization of bound water in skin hydrators prepared with and without a 3D3P interpenetrating polymer network. G.P. Majewski, K. Rodan, K. Fields, T.J. Falla. Skin Res Technol. 2018; 25: 150-157.
- Majewski G, Rodan K, Fields K, Ong D, Falla TJ. Hydrating the Skin with a Novel Interpenetrating Polymer Network. J. Clinic. Exper. Cosme. Dermatol. 2017; 1: 003.
- Rodan K, Fields K and Falla TJ. Efficacy of a twice daily, 3-step, over the counter skincare regimen for the treatment of acne vulgaris. Clinical, Cosmetic and Investigational Dermatology. 2017; 10: 3-9.
- Rodan K, Fields K and Falla TJ. Bioactive Peptides. In: Cosmeceuticals and Cosmetic Practice. Ed: Patricia K. Farris. 2014. Wiley Blackwell, Chichester England.
- Farwick M, Grether-Beck S, Marini A, Maczkiewitz U, Lange J, Köhler T, Lersch P, Falla T, Felsner I, Brenden H, Jaenicke T, Franke S, Krutmann J. Bioactive tetrapeptide GEKG boosts extracellular matrix formation: in vitro and in vivo molecular and clinical proof. Exp Dermatol. 2011 Jul;20(7):602-4.
- Falla TJ, Zhang L. Efficacy of hexapeptide-7 on menopausal skin. J Drugs Dermatol. 2010 Jan;9(1):49-53.
- Zhang L, Falla TJ. Potential therapeutic application of host defense peptides. Methods Mol Biol. 2010;618:303- 27.
- Zhang L, Falla TJ. Cosmeceuticals and peptides. Clin Dermatol. 2009 Sep-Oct;27(5):485-94.
- Fields K, Falla TJ, Rodan K, Bush L. Bioactive peptides: signaling the future. J Cosmet Dermatol. 2009. Mar;8(1):8- 13.
- Zhang L, Falla TJ. Host defense peptides for use as potential therapeutics. Curr Opin Investig Drugs. 2009 Feb;10(2):164-71.
- Borders DB, Leese RA, Jarolmen H, Francis ND, Fantini AA, Falla T, Fiddes JC, Aumelas A. Laspartomycin, an acidic lipopeptide antibiotic with a unique peptide core. J Nat Prod. 2007 Mar;70(3):443-6.
- Zhang L, Falla TJ. Antimicrobial peptides: therapeutic potential. Expert Opin Pharmacother. 2006 Apr;7(6):653- 63.
- Zhang L, Parente J, Harris SM, Woods DE, Hancock RE, Falla TJ. Antimicrobial peptide therapeutics for cystic fibrosis. Antimicrob Agents Chemother. 2005 Jul;49(7):2921-7.
- Lee PH, Rudisill JA, Lin KH, Zhang L, Harris SM, Falla TJ, Gallo RL. HB-107, a nonbacteriostatic fragment of the antimicrobial peptide cecropin B, accelerates murine wound repair. Wound Repair Regen. 2004 May- Jun;12(3):351-8.
Selected Patents
- US 7,390,787: Compositions and methods for treating infections using analogs of indolicidin
- US 7,696,174: Short bio-active peptides for cellular and immunological modulation
- US 8,071,555: Protective skincare peptides
- US 8,110,658: Peptide fragments for inducing synthesis of extracellular matrix
- US 8,597,902: Peptide protection against ultraviolet light toxicity
- US 9,487,558: Short bio-active peptides for promoting wound healing
- US 9,511,042: N-acyl amino acid derivatives for treating skin conditions such a cellulite
- US 10,722,488: Hest G-18-0 and benzoyl peroxide compositions and methods for using the same
- US 10,722,443: Moisturizing compositions and uses thereof
- US 11,318,077: Retinaldehyde containing compositions and methods of use
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